![]() ![]() The conversion from DNA to protein and protein to DNA (reverse translate) can be done within a few minutes. Translations into Proteins:Ī much needed tool for executing certain time-taking processes. So before spending your chemical resources in the wet lab experiments, you can give it practice on SnapGene. It allows the simulation of Agarose gel, PCR Amplification, Restriction digestion, etc. Easy file conversions among different Software such as- ApE, CLC Bio, Clone Manager, DNA Strider, DNADynamo, DNASIS, DNAssist, DNASTAR Lasergene, GenBank / DDBJ, Geneious, etc. Another beneficial feature is that methyl group is sensitized very quickly. You can view the details of the enzymes in details. You can design your own sets of enzymes and use according to the need and save for later use. There are some predefined sets of enzymes that are either provided by the tool developer company or through the virtual cutter. This feature saves a lot of time and energy on the user’s end. Virtual PCR and Mutagenesis:Ī very interesting feature since Polymerase Chain Reactions can be simulated virtually. It joins/anneals two oligos together to give rise to double stranded Sequences. Very efficient in developing primers for virtual PCR. It performs Gibson Assembly and NEBuilder HiFi Assembly too. It can perform various types of cloning such as- Restriction Cloning, In-Fusion Cloning, Gateway Cloning, TA & GC Cloning, TOPO Cloning and many more. The most commonly used and applied feature of SnapGene. ![]() SnapGene supports the ribosomal slippage as well. Manually choose the codons as an alternate. You can number the translations sophisticatedly. You can manually annotate the specific or novel features of the sample. You can create, edit sequences, and annotate them automatically for common features. The basic and necessary features of SnapGene. Isn’t that interesting and creative! Edits and Annotations: You can view, edit and annotate the DNA or Protein sequences. Firstly, there are multiple view options for DNA and Protein sequences. You would fall for the intricate designing and viewing choices. Contig Assembly is an essential feature exhibited by SnapGene. You can choose from Clustal Omega, MAFFT, MUSCLE, and T-Coffee. The choice to choose the alignment algorithm is also provided. Pairwise alignment and multiple sequence alignments between DNA sequences and Protein sequences can be performed. You can verify the cloning or mutagenesis that you have performed. You can align the complementary DNA to any chromosome. It allows the alignment of DNA sequences with reference genomes or any other genome you can choose manually. Undergraduate students, post graduate students, PhD scholars, professors, lecturers, academic professionals, corporates and scientists can use the software.Ī typical basic feature for any type of software tool. The SnapGene tool can be used by any person who has basic computational knowledge and clear understanding of biological concepts. The tool is handy and can be used by people from various interdisciplinary science fields. They have applied the appropriate algorithms and right codes for easiness in use. Who’s it for?Ĭomputational Biologists and Professional Programmers have designed the tool with a lot of sophistication. You will know about its remarkable features in the upcoming sections. However, in SnapGene, Molecular cloning is the foremost feature and elaborative too. In Geneious, this process of cloning is a one-step process. Well, when I tried to compare SnapGene with other Molecular cloning tool such as Geneious, I found that SnapGene is far more elaborate and extensive. ![]()
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